Website University of Reims
Skills area: Chemistry, organic Chemistry, photochemistry, physical chemistry, chemical engineering.
Our research group is part of the Institut de Chimie Moléculaire de Reims localized at the University of Reims (ICMR, UMR 7312). We have an outstanding experience synthetic organic photochemistry. Currently, worldwide activities in this field are growing (Chem. Rev. 2008, 108, 1052; ChemSusChem 2012, 5, 352; Chem. Rev. 2016, 116, special issue 17 “Photochemistry in organic synthesis”). Such transformations are also interesting in the context of sustainable (green) chemistry (see for example: Photochem. Photobiol. Sci. 2012, 11, 1613. In this regard chemical engineering of such reactions is investigated in order to perform them on industrial scale and in an efficient way.
The proposed research of the PhD student is carried out in the context of the ANR (The French National Reseach Agency) project “Imine Photochemistry: Photoinduced radical reactions of imines” (IMPHOCHEM). It deals with organic reactions of photochemically excited imines (J. Org. Chem. 2018, 83, 1867). Different mechanisms of hydrogen atom transfer in these photochemical reactions will be characterized. The selectivity, in particular the stereoselectivity, will be studied under different conditions. The reactions will be applied to the synthesis of heterocyclic compounds possessing a biologically active compounds. Organic synthesis and the structure determination of new compounds are important parts of the daily work. With the project partners, the reactions will be optimized for being carried out in micro-reactors and under continuous flow conditions. Physicochemical or theoretical studies will also be performed in cooperation. Beyond our research group, a research group of from Toulouse (Laboratoire de génie chimique, LGC, UMR 5503 (project partner) and from the Hiroshima University, Japan (external project partner) are involved in the project.
Profile of the candidate:
Solid experience in organic chemistry, open spirit for interdisciplinary research (photochemistry, photocatalysis, chemical engineering), autonomy, team work.
Duration: 36 months
Annual salary (net): 17000 € (Employer: CNRS, Funding: ANR)
Workplace: Université de Reims Champagne-Ardenne, Reims, France.
Application will proceed first by e-mail by sending a detailed CV, records of master and bachelor degrees as well as two names of referees.